Status:
COMPLETED
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings.
Lead Sponsor:
Gonzalo Hernandez Martinez
Conditions:
Weaning Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Hypothesis: 1. In patients with less than 4 high risk factors for reintubation excluding body mass index \>30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk f...
Detailed Description
Discontinuation of mechanical ventilation is a three-step process including: 1. \- Readiness testing. It evaluates the criteria to determine whether a patient might be able to be successfully and...
Eligibility Criteria
Inclusion
- Patients on mechanical ventilation for more than 24 hours with \>= positive end-expiratory pressure 10.
- Patients with up to three high risk factors for extubation failure excluding hypercapnia during the spontaneous breathing trial and obese patients (BMI \>30).
- Patients fulfilling weaning criteria expected to have a spontaneous breathing trial in the following 24 hours.
- Patients expected to be prevented with high-flow oxygen therapy after extubation.
Exclusion
- \<18 years old.
- Pregnant women.
- Tracheostomized patients.
- Accidental or self-extubated patients.
- Obese (BMI \>30) or hypercapnic patients during the spontaneous breathing trial.
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2023
Estimated Enrollment :
940 Patients enrolled
Trial Details
Trial ID
NCT04758546
Start Date
March 1 2021
End Date
March 31 2023
Last Update
April 6 2023
Active Locations (1)
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1
Hospital Virgen de la Salud
Toledo, Castille-La Mancha, Spain, 45007