Status:
TERMINATED
Insulin and Muscle Fat Metabolism
Lead Sponsor:
Oregon State University
Conditions:
Overweight and Obesity
Insulin Resistance
Eligibility:
All Genders
30-55 years
Phase:
NA
Brief Summary
Our objective in this study is to identify the extent to which insulin drives the accumulation of lipids in skeletal muscle of humans. We will test the hypothesis that 4-hours of mild hyperinsulinemia...
Eligibility Criteria
Inclusion
- Age 30-55 years
- Body mass index (BMI) 18-45 kg/m2
- Sedentary (\<1 hour of planned exercise per week)
Exclusion
- Regular exercise (\>1 hour of planned exercise per week)
- Smoking, tobacco or nicotine use within the last 1-year
- Fasting glucose \>126mg/dL
- Hypertension (systolic pressure \>140 mmHg or diastolic pressure \>90 mmHg)
- Chronic metabolic or cardiovascular health conditions
- Pregnant, nursing, irregular menses or post-menopausal
- Lidocaine allergy
- Certain medications
- Diminished capacity for consent
Key Trial Info
Start Date :
February 22 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 7 2022
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT04759872
Start Date
February 22 2021
End Date
June 7 2022
Last Update
June 10 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Oregon State University
Corvallis, Oregon, United States, 97331