Status:

COMPLETED

The Effect of Anesthesia on Cerebral Oxygenation

Lead Sponsor:

Karadeniz Technical University

Conditions:

One-Lung Ventilation

Thoracic Surgery

Eligibility:

All Genders

18-80 years

Brief Summary

One-lung ventilation (OLV) may cause negative changes in the oxygenation of cerebral tissue which results in postoperative cognitive dysfunction. The aim of this prospective study was to compare the p...

Detailed Description

One-lung ventilation (OLV) is a commonly used technique in thoracic surgeries. In thoracic surgeries performed with OLV, there may be changes in cerebral tissue oxygenation depending on both patient p...

Eligibility Criteria

Inclusion

  • Patients in American Society of Anesthesiology (ASA) classification I and II
  • Patients who would undergo thoracic surgery with one-lung ventilation (OLV)
  • thoracic surgeries with one-lung ventilation (OLV) that will take at least 45 minutes

Exclusion

  • Patients in ASA classification III and higher
  • Emergency surgery
  • Patients with known allergy to drugs used in the study
  • Patients in New York Heart Association classification III-IV
  • severe metabolic, renal, hepatic, central nervous system diseases, alcohol or drug addiction
  • multiple trauma, coagulapathy, cerebral disease, dementia, hearing impairment and imperception
  • severe obesity (a body mass index (BMI) of ≥ 35)
  • patients with a peripheral oxygen saturation below 90 during one lung ventilation

Key Trial Info

Start Date :

March 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 20 2020

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04760262

Start Date

March 1 2017

End Date

January 20 2020

Last Update

February 18 2021

Active Locations (1)

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Karadeniz Technical University

Trabzon, Turkey (Türkiye), 61080