Status:
COMPLETED
Antiseptic Irrigation for Pleural Infection
Lead Sponsor:
Alexandria University
Conditions:
Pleural Infection
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
The antiseptic povidone-iodine can safely be instilled into the pleural for the purpose of pleurodesis. Pleural irrigation with antiseptics is used in adults with open drainage for chronic empyema and...
Detailed Description
Pleural infection is a condition that requires hospitalization for management and is associated with significant in-hospital morbidity and mortality. Predictors of poor outcome include advancing age, ...
Eligibility Criteria
Inclusion
- All adult patients admitted to hospital with pleural infection and had a chest tube inserted for treatment of the infection. Pleural infection will be defined by the presence of one of the following: a) the presence of pus in the pleural space; b) positive pleural fluid gram stain or culture; or c) pleural fluid pH \< 7.2 or pleural fluid glucose \< 40 mg/dL in the setting of acute respiratory infection.
- Pleural collection is unilocular on pre-drainage imaging. Presence of septations on ultrasound examination is allowed.
Exclusion
- Known or suspected thyroid disease
- Allergy to iodine
- Persistent large collection on follow up imaging 24-48 of post tube insertion that requires another drainage procedure
Key Trial Info
Start Date :
March 4 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 15 2021
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT04761133
Start Date
March 4 2021
End Date
August 15 2021
Last Update
August 31 2022
Active Locations (1)
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1
Alexandria University Faculty of Medicine
Alexandria, Egypt