Status:
UNKNOWN
Quantitative MRI of Bone Marrow Fat Fraction in Patients With Trepanobiopsy
Lead Sponsor:
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Conditions:
Aplastic Anemia
Aplastic Anemia Idiopathic
Eligibility:
All Genders
6-18 years
Phase:
NA
Brief Summary
The study is aimed to find correlation between the assessment of cellularity according to trepanobiopsy data and the results of measuring MRI parameters.
Detailed Description
The ratio of fat to water in the bone marrow depends on the cellularity of the bone marrow. In addition to the water/fat ratio in bone marrow there are also other parameters for quantitative MRI asses...
Eligibility Criteria
Inclusion
- presence of indications for performing trepanobiopsy:
- aplastic anemia
- chronic myeloproliferative disease
- reactive changes in hematopoiesis
Exclusion
- Refusal to sign an informed consent to participate in a clinical trial
- Presence of contraindications for MRI examination
- Extremely serious condition of the patient at the time of inclusion in the study.
Key Trial Info
Start Date :
February 16 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04761965
Start Date
February 16 2021
End Date
January 1 2024
Last Update
March 8 2023
Active Locations (1)
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1
Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology
Moscow, Samory-Mashela,1, Russia, 11198