Status:
UNKNOWN
Power Training in Older Multiple Sclerosis Patients
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
University of Southern Denmark
University of Copenhagen
Conditions:
Multiple Sclerosis
Sclerosis
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The study seeks to investigate whether 24 weeks of power training has neuroprotective effects in older PwMS. Additional purposes are to examine the effects of 24 weeks power training on physical funct...
Detailed Description
Over the past 3-4 decades, the lifespan among people with multiple sclerosis (MS) has increased substantially. Today more than one-third of all people with MS are 60 years or older. With advanced age,...
Eligibility Criteria
Inclusion
- ≥ 60 years of age.
- Clinically diagnosed with MS according to the McDonald criteria (48).
- Having an EDSS ≤ 6.5.
- able to transport themselves to the testing at Aarhus University and Aarhus University Hospital.
- able to transport themselves to training, if randomized to the PRP group.
Exclusion
- having comorbidities (cardiovascular, respiratory, orthopedic, or other neurological diseases than MS) affecting PRP participation or MRI scans.
- having a pacemaker.
- having metallic implant(s) that prevents MRI scans.
- having untreated osteoporosis; t-score below -2.5 and a history of low energy facture or t-score below -3.0.
- participating in more than two sessions per week of structured PRE and have done so for the past 3 months.
- Are cognitively impaired at a level expected to prevent the participant from understanding training and testing instructions.
Key Trial Info
Start Date :
December 7 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 28 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04762342
Start Date
December 7 2020
End Date
August 28 2024
Last Update
June 23 2023
Active Locations (1)
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1
Tobias Gæmelke
Aarhus C, Denmark, 8000