Status:
RECRUITING
Learning Study: Improving Vision in Adults With Macular Degeneration
Lead Sponsor:
University of Waterloo
Collaborating Sponsors:
The Hong Kong Polytechnic University
Conditions:
Macular Degeneration
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to test whether a kind of brain stimulation called anodal transcranial direct current stimulation (a-tDCS) can be combined with perceptual learning to improve the ability ...
Detailed Description
This study will be carried out in Ontario, Canada (University of Waterloo) and Hong Kong (The Hong Kong Polytechnic University). There are two conditions: Active brain stimulation + perceptual trainin...
Eligibility Criteria
Inclusion
- Diagnosis of AMD (age 60+) or JMD (current age 18+).
- Visual acuity (VA); between 6/9-6/96 in the better eye
- Best-corrected near visual acuity of 4.0M at 40 cm or better in the better eye
- Stable vision in previous 3 months (patient report)
- Central vision loss
Exclusion
- Diagnosed dementia.
- Not fluent in reading English (Waterloo) or Chinese characters (Hong Kong).
- Any ocular surgery (including anti-vegF injections) within the duration of the study, except for: A. Chronic and continuous injections for at least 1 year. B. Injections stopped at least 2 months before participation. C. Injections in the untested eye
- Ocular pathology other than JMD or AMD that can significantly reduce central vision. Example: mild cataract of grade 2 or below is acceptable
- Severe hearing impairment.
- Contraindications for brain stimulation
Key Trial Info
Start Date :
February 13 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04762368
Start Date
February 13 2021
End Date
December 1 2026
Last Update
June 4 2025
Active Locations (2)
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1
University of Waterloo
Waterloo, Ontario, Canada, N2L 3G1
2
The Hong Kong Polytechnic University
Hung Hom, Kowloon, Hong Kong