Status:
UNKNOWN
Prevention and Treatment of Complications of Endovascular Methods in Patients With Malignant Liver Tumors
Lead Sponsor:
Central Clinical Hospital RZD-Medicine, Russian Federation
Conditions:
Hepatic Cancer
Metastatic Cancer
Eligibility:
All Genders
18+ years
Brief Summary
In the structure of malignant liver lesions, two main groups are distinguished - primary liver cancer and metastatic liver damage. The five-year survival rate of patients with malignant liver tumors d...
Eligibility Criteria
Inclusion
- Aged over 18 years old;
- Histologically confirmed diagnosis of liver cancer or metastatic liver disease;
- Patients who have not received systemic antitumor therapy within the last 6 months
Exclusion
- Metachronous (within 3 years) or synchronous other oncological disease with the exception of healed carcinoma in situ;
- The volume of liver damage according to computed tomography is more than 60%;
- Increase in the level of transaminases by more than 2 times;
- The level of bilirubin is more than 50 μmol / l;
- Heart failure stage II B-III, Functional Class III-IV;
- The presence of uncorrected coagulopathy;
- Renal failure stage III-IV;
- Ascites 2-3 degrees;
- The general condition of the patient is below 60% on the Karnofsky index and above 2 points on the Eastern Cooperative Oncology Group (ECOG) scale;
- Liver damage - more than 7 points on the Child-Pugh scale;
- Damage to the central nervous system;
- Anemia of severe severity;
- Pregnancy;
- Active autoimmune disease;
- Presence of HIV infection, active forms of tuberculosis;
Key Trial Info
Start Date :
January 12 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 12 2023
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT04764409
Start Date
January 12 2021
End Date
December 12 2023
Last Update
February 21 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Central Clinical Hospital RZD-Medicine, Russian Federation
Moscow, Moscow's Oblast, Russia, 129128