Status:
ACTIVE_NOT_RECRUITING
Functioning of Elder Muscle; Understanding Recovery
Lead Sponsor:
University of Nottingham
Collaborating Sponsors:
Nottingham Biomedical Research Centre
Conditions:
Frailty Syndrome
Eligibility:
All Genders
65+ years
Brief Summary
As people get older, the amount of skeletal muscle in the body can decrease. When the amount of this muscle in the body gets very low, there is an increased risk of falling, and not only is recovery t...
Detailed Description
Sarcopenia is the age-associated loss of skeletal muscle mass, muscle quality and strength, and is a contributive factor to frailty in older individuals. Meta-analyses suggest that individuals with sa...
Eligibility Criteria
Inclusion
- Clinical Frailty Score (assessed as part of standard care) ≥ 4
- Fractured hip, sustained following a fall, that requires surgery
- Good understanding of spoken and written English language
- Able to give informed consent, or availability of a legally acceptable surrogate to provide consent
Exclusion
- Those who fell and sustained their hip fracture greater than 12 hours prior to hospitalisation.
- Those who have fallen and sustained a hip fracture whilst an in-patient in hospital
- Those who sustained the hip fracture as a result of high impact trauma (e.g. road traffic accident)
- Surgery carried out later than 96 hrs after fall
- Chronic neurological, inflammatory or musculoskeletal disorders which result in muscle wasting, e.g. Multiple sclerosis, muscular dystrophy, rheumatoid arthritis
- Any co-morbidity which precludes hip surgery
- Those with a compromised swallowing reflex which would prevent the participant from taking fluids orally, will be excluded.
- Those taking diabetes medication
Key Trial Info
Start Date :
January 4 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2025
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04764617
Start Date
January 4 2021
End Date
December 31 2025
Last Update
September 3 2025
Active Locations (1)
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1
Queens Medical Centre; Department of Orthopaedics
Nottingham, United Kingdom, NG72UH