Status:

ACTIVE_NOT_RECRUITING

A PMCF Study in Patients With Infrarenal Aortic Aneurysm Treated With the E-tegra Stent Graft System

Lead Sponsor:

JOTEC GmbH

Conditions:

Vascular Aneurysm

Eligibility:

All Genders

18+ years

Brief Summary

The EASY post-market clinical follow-up study is undertaken to demonstrate safety and clinical performance of the E-tegra Stent Graft System used in endovascular treatment of infrarenal aortic aneurys...

Detailed Description

In this study, patients will be observed who receive an E-tegra Stent Graft for the treatment of infrarenal aortic aneurysm. The E-tegra Stent Graft will be implanted at the discretion of the treating...

Eligibility Criteria

Inclusion

  • Age ≥ 18
  • Patient must have an infrarenal aortic aneurysm with diameter ≥ 50 mm in females and ≥ 55 mm in males, or infrarenal aortic aneurysm with 40-50 mm that has increased in size by ≥ 1 cm per year
  • Patient is elegible for treatment inside the instructions for use of the E-tegra Stent Graft System
  • Patient is able and willing to undergo follow-up imaging and examinations prior to discharge from the hospital, at 30 days and 12 months, and annually thereafter until 5 years follow-up
  • Patient understands and has signed the Informed Consent Form prior to intervention
  • Patient has a life expectancy of at least 5 years

Exclusion

  • Patient with severe calcification or thrombi in the proximal sealing zone
  • Patient with infectious aneurysm
  • Patient with inflammatory aneurysm
  • Patient with pseudoaneurysm
  • Patient with symptomatic aneurysm
  • Patient with ruptured or traumatic aneurysm
  • Patient with suprarenal, juxtarenal, or pararenal aneurysm
  • Patient with aortic dissection
  • Patient with a reversed conical neck that is defined as a \> 3 mm distal increase over a 15 mm length
  • Patient in which the E-tegra Stent Graft System is used in combination with proximal or distal extenders of another company.
  • Patient who is planned to be treated with an adjunctive aortic bare metal stent or a fenestrated stent graft
  • Patient who is planned to be treated with a chimney / chimneys in the renal or visceral vessels
  • Patient who is planned to be treated with an iliac branch device or parallel grafts in the iliac vessels
  • Patient with genetic connective tissue disease (e.g. Marfan syndrome or Ehlers-Danlos syndrome)
  • Patient with eGFR \< 45 ml/min/1.73 m2 before the intervention
  • Patient had or planned to have a major surgical or interventional procedure within 30 days before or 30 days after the planned implantation of the E-tegra Stent Graft System
  • Patient with other medical condition that may cause the patient to be non-compliant with the protocol, confound the results, or is associated with a limited life expectancy of less than five years (i.e. heart failure, active malignancy (progressive, stable or partial remission))
  • Patient who has been enrolled in another active clinical trial that does not allow inclusion in this trial

Key Trial Info

Start Date :

March 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2029

Estimated Enrollment :

151 Patients enrolled

Trial Details

Trial ID

NCT04765176

Start Date

March 1 2021

End Date

October 1 2029

Last Update

July 25 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Rijnstate Hospital

Arnhem, Netherlands, 6815