Status:
ACTIVE_NOT_RECRUITING
WashIn /WashOut Procedure To Prevent Agitation During Recovery After Inhalational Anesthesia With Sevoflurane
Lead Sponsor:
I.M. Sechenov First Moscow State Medical University
Conditions:
Agitation, Emergence
Postoperative Delirium
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Inhalation anesthesia is the most frequently used technique and is performed in around 70% of surgeries worldwide. Sevoflurane is the most frequently used halogenated anesthetic and is used in 2/3 of ...
Detailed Description
Inhalation anesthesia is the most frequently used technique and is performed in around 70% of surgeries worldwide. Sevoflurane is the most frequently used halogenated anesthetic and is used in 2/3 of ...
Eligibility Criteria
Inclusion
- Written informed consent from participants
- Age ≥ 18 years
- Planned open abdominal surgery
- General anesthesia
Exclusion
- Pregnant patients and breastfeeding patients
- Mental disorders
- Epilepsy, Parkinson disease, Alzheimer, peripheral nerve and neuromuscular junction pathology (amyotrophic lateral sclerosis, Guillain-Barre Syndrome, myasthenia gravis et cet.)
- Use of antidepressants, antipsychotics, sedatives, psychoactive drugs within a month before surgery.
Key Trial Info
Start Date :
March 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 25 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04765488
Start Date
March 10 2021
End Date
February 25 2026
Last Update
July 8 2025
Active Locations (3)
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1
Moscow Scientific Clinical Center
Moscow, Russia, 111123
2
Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy
Moscow, Russia, 129110
3
Clinical hospital №1 of the I.M. Sechenov First Moscow State Medical University (Sechenov University)
Moscow, Russia