Status:

COMPLETED

ACE2 Gender Differences in Stroke With COVID-19

Lead Sponsor:

Fondazione Don Carlo Gnocchi Onlus

Conditions:

Neurologic Manifestations

Eligibility:

All Genders

18-90 years

Brief Summary

The new coronavirus SARS-CoV-2, causes the COVID-19 infection, which showed a form of neurovirulence involving the Central and peripheral Nervous Systems \[Baig et al, 2020\]. In a mouse model for hum...

Detailed Description

A new coronavirus was identified in December 2019 in Wuhan, China as the causative agent of "Severe Acute Respiratory Syndrome" (SARS-CoV-2), a viral lung infection indicated by the acronym COVID-19 (...

Eligibility Criteria

Inclusion

  • stroke patients (hemorrhagic or ischemic) documented through Magnetic Resonance Imaging (MRI) or Computed Tomography (CT);
  • NeuroCOVID19 stroke patients with double nasopharyngeal swab negative after 24 hours for SARS-Cov2.
  • latency time within 6 months after stroke event;
  • sufficient cognitive and language skills to understand the instructions related to the administration of the assessment scales and to sign informed consent;

Exclusion

  • behavioral and cognitive disorders that may interfere with the therapeutic activity;
  • other orthopaedic or neurological complications that may interfere with the rehabilitation protocol;
  • inability to understand and sign informed consent;

Key Trial Info

Start Date :

September 4 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 31 2023

Estimated Enrollment :

77 Patients enrolled

Trial Details

Trial ID

NCT04766645

Start Date

September 4 2020

End Date

January 31 2023

Last Update

July 18 2023

Active Locations (1)

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Fondazione Don Carlo Gnocchi

Rome, Italy, 00168