Status:

ACTIVE_NOT_RECRUITING

Comparison Study of LMX4 Cream Versus J-Tip Needle-Free Injection System With Lidocaine for In-Office PAT for Clubfoot

Lead Sponsor:

Vanderbilt University Medical Center

Conditions:

Clubfoot

Eligibility:

All Genders

Up to 6 years

Phase:

PHASE4

Brief Summary

Infants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting. This procedure is commonly performed in the office with a ...

Detailed Description

Clubfoot is a common congenital birth deformity, with a prevalence of 1 in 1000 live births. If left untreated, clubfoot can cause significant disability. Treatment of clubfoot has evolved over severa...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Clubfoot patients less than 6 weeks of age at start of casting
  • Patients presenting to Vanderbilt DOT 4 Clinic for care
  • Patients undergoing in-clinic Achilles Tenotomy
  • Exclusion Criteria
  • Clubfoot patients greater than 6 weeks of age at the start of casting
  • Previous clubfoot treatment
  • Patients with a neuromuscular condition (spina bifida, caudal regression syndrome, arthrogryposis, etc.)
  • In-office TAL is not recommended by treating physician due to patient factors such as age or size

Exclusion

    Key Trial Info

    Start Date :

    June 1 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    January 1 2026

    Estimated Enrollment :

    94 Patients enrolled

    Trial Details

    Trial ID

    NCT04766684

    Start Date

    June 1 2021

    End Date

    January 1 2026

    Last Update

    June 8 2025

    Active Locations (1)

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    Vanderbilt Children's Orthopaedics

    Nashville, Tennessee, United States, 37232