Status:
RECRUITING
sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.
Lead Sponsor:
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Collaborating Sponsors:
Fundacion Clinic per a la Recerca Biomédica
Conditions:
Preeclampsia
Intrauterine Growth Restriction
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
* Preeclampsia (PE) affects \~5% of pregnancies. Although improved obstetrical care has significantly diminished associated maternal mortality, PE remains a leading cause of maternal morbidity and mor...
Detailed Description
Finding an effective prediction and prevention for term PE remains an unsolved challenge. From previous recent evidence it seems clear that prediction very close to term may achieve a high detection r...
Eligibility Criteria
Inclusion
- Nulliparous women
- Singleton pregnancies
- \>18 years old
- 0-36.6 weeks of gestation
- Maternal written consent form
Exclusion
- Fetuses/neonates with major malformations or genetic anomalies that could modify the timing of delivery or has an impact on obstetric outcome
- Suspected fetal growth restriction (estimated fetal weight \<3 centile or between the 3rd and 10th centile together with abnormal Doppler in the mean uterine artery Doppler pulsatility index, or in umbilical artery pulsatility index or in the middle cerebral artery or in the cerebral umbilical index (CPR))
- Participation in another interventional study that could modify the timing of delivery.
Key Trial Info
Start Date :
March 2 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
9132 Patients enrolled
Trial Details
Trial ID
NCT04766866
Start Date
March 2 2021
End Date
December 31 2026
Last Update
February 19 2025
Active Locations (21)
Enter a location and click search to find clinical trials sorted by distance.
1
CHU Liège
Liège, Belgium
2
Clinica del Prado SAS
Bogotá, Colombia
3
Institute for the Care of Mother and Child
Prague, Czechia
4
Medicina Fetal Quito
Quito, Ecuador