Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
ID04767074

Non-pharmacological Cough Control Therapy with Pulmonary Rehabilitation for Chronic Cough in Interstitial Lung Disease A Feasibility Study Evaluating Virtual Educational and Self-Management Sessions

Led by West Park Healthcare Centre · Updated on 2025-04-03

24

Participants Needed

2

Research Sites

273 weeks

Total Duration

On this page

Sponsors

W

West Park Healthcare Centre

Lead Sponsor

S

St. Joseph's Healthcare Hamilton

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a non-drug cough control therapy as an addition to pulmonary rehabilitation for adults with interstitial lung disease (ILD) who experience chronic cough lasting more than 8 weeks. Chronic cough in ILD causes significant physical, psychological, and social challenges, and currently, no approved medications effectively treat this symptom. This study aims to explore whether this cough control therapy is feasible and more effective than pulmonary rehabilitation alone in improving quality of life, reducing cough intensity, and lessening fatigue symptoms. Participants will join an outpatient pulmonary rehabilitation program that includes aerobic and strength exercises, disease-specific education, and self-management. Two weeks before pulmonary rehabilitation ends, they will begin the non-pharmacological cough control therapy consisting of four virtual sessions lasting 45 to 60 minutes each. These sessions cover cough assessment, education on cough mechanisms, cough suppression techniques, breathing pattern retraining, and laryngeal hygiene strategies, delivered through an online platform called Zoom Healthcare Plan. During the study, researchers will track how many eligible patients enroll and complete the intervention, session attendance, and any side effects. They will assess outcomes using questionnaires on cough severity, lung disease quality of life, fatigue, breathlessness, and cough sensitivity, along with global change ratings and participant satisfaction interviews. The average study duration is one year, with evaluations before and after the intervention to measure feasibility and effectiveness of the therapy.

CONDITIONS

Official Title

A Non-pharmacological Cough Control Therapy

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Confirmed diagnosis of any interstitial lung disease (ILD) by a physician
  • Chronic cough lasting more than 8 weeks
  • Age between 18 and 85 years
Not Eligible

You will not qualify if you...

  • Moderate or large sputum production reported by the patient
  • Respiratory condition exacerbation in the past month
  • Upper respiratory tract infection in the past month
  • Use of angiotensin-converting enzyme inhibitor medication
  • Changes in prescribed medication in the previous month
  • Evidence of traction bronchiectasis on HRCT scan
  • Medical conditions preventing exercise training
  • Inability to read or speak English or provide informed consent

AI-Screening

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Trial Site Locations

Total: 2 locations

1

St. Joseph's Healthcare Hamilton

Hamilton, Ontario, Canada

Actively Recruiting

2

West Park Healthcare Centre

Toronto, Ontario, Canada, M6M 2J5

Actively Recruiting

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Research Team

A

Ana Oliveira, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Published Research Related To This Trial

Physiotherapy, and speech and language therapy intervention for patients with refractory chronic cough: a multicentre randomised control trial.

Sarah A F Chamberlain Mitchell, Rachel Garrod, Lynne Clark...

https://pubmed.ncbi.nlm.nih.gov/27682331