Status:
ACTIVE_NOT_RECRUITING
Quantitative Imaging of Brain Glymphatic Function in Humans
Lead Sponsor:
Vanderbilt University Medical Center
Conditions:
Parkinson Disease
Eligibility:
All Genders
55-80 years
Phase:
EARLY_PHASE1
Brief Summary
Recent immunological and physiological studies have provided evidence in support of a central nervous system (CNS) lymphatic drainage system in vertebrate animals, and preliminary evidence has suggest...
Detailed Description
The proposal involves magnetic resonance imaging (MRI) of healthy volunteers and patient volunteers suffering from Parkinson's disease. As part of the research study, volunteers will undergo 1-2 non-i...
Eligibility Criteria
Inclusion
- diagnosis of Parkinson's Disease or controls
- willing to participate in PET and MRI imaging
Exclusion
- recent stimulant use
- unstable diabetes
- prior stroke
- claustrophobia
- prior cancer treatment with chemotherapy
- history of traumatic brain injury
- any unstable medical condition
Key Trial Info
Start Date :
April 15 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT04768101
Start Date
April 15 2020
End Date
December 31 2025
Last Update
June 17 2025
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37212