Status:
COMPLETED
Combined Physical-cognitive Exercise and Dietary Intervention for Postmenopausal Obese Women
Lead Sponsor:
Chiang Mai University
Conditions:
Obesity
Eligibility:
FEMALE
45-59 years
Phase:
NA
Brief Summary
This study aims to examine the effects of dietary intervention combined with physical-cognitive exergaming on cognitive performance and circulating biomarkers of obese postmenopausal women. It is hypo...
Detailed Description
An association between obesity and cognitive impairment has been consistently reported. The risk of having dementia in later life is about 74% higher for middle-aged obese individuals than those with ...
Eligibility Criteria
Inclusion
- obese women (body mass index (BMI) ≥ 25 kg/m2 with waist-to-hip ratio (WHR) ≥ 0.80)
- post-menopausal (self-reported menstrual characteristics (last menstruation \> 1 year) or confirmed by blood follicular stimulating hormone (FSH) level ( \> 20 IU/L) and estradiol level ( ≤ 30 pg/ml))
- sedentary lifestyle (exercise \< 1 hr./wk.)
- normal range of the Mental State Examination T10 (MSET10) score
- at least 6 years of education
- own a mobile phone that supports application platform
- able to comply with the study schedule and procedures
Exclusion
- have medical conditions that would be unsafe to exercise or have been diagnosed with neurological conditions (e.g. Parkinson's disease, stroke, multiple sclerosis) that affect cognition and mobility
- have weight variation ( \> 5 kilogram in 3 months)
- have other dietary restrictions (e.g. vegetarianism and veganism)
- have depressive symptoms defined as a score ≥ 11 on Hospital Anxiety Depression Scale (HADS)
- have an uncorrected visual or hearing impairment
- receive hormonal replacement therapy
Key Trial Info
Start Date :
September 26 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 5 2022
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT04768725
Start Date
September 26 2021
End Date
December 5 2022
Last Update
February 14 2023
Active Locations (1)
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1
Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University
Chiang Mai, Thailand, 50200