Status:
RECRUITING
Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
Lead Sponsor:
Tulane University
Conditions:
Atrial Fibrillation
Stroke
Eligibility:
All Genders
18-120 years
Phase:
NA
Brief Summary
Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance ...
Detailed Description
The investigators propose a cross-sectional cohort study, where individuals with no history of AF and with a Congestive heart failure, Hypertension, Age ≥ 75 years, Diabetes mellitus, Stroke or transi...
Eligibility Criteria
Inclusion
- Male or female patients
- 18 Years and older
- No history of atrial fibrillation
- CHA2DS2VASC score ≥3
- History pf type II diabetes
- History of congestive heart failure or a history of transient ischemic attack (TIA)/stroke without an otherwise defined stroke etiology such as large vessel or small vessel disease
Exclusion
- History of atrial fibrillation
- Patients who had a clinically symptomatic acute stroke within the last 30-days
- Any health-related gadolinium/MRI contraindication (including previous allergic reaction to Gadolinium, pacemakers, defibrillators, other devices/implants contraindicated for MRI)
- Estimated glomerular filtration rate (eGFR) cutoff in patients with Chronic kidney disease (CKD) where gadolinium cannot be used equals an eGFR \<30 ml/min
- Weighing \> 300 lbs (as CMR image quality decreases due to increased body mass index)
- Current pregnancy or breastfeeding
- Cognitive impairment preventing the patient from giving an informed consent
Key Trial Info
Start Date :
April 26 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04769310
Start Date
April 26 2021
End Date
January 1 2026
Last Update
December 20 2024
Active Locations (1)
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1
Tulane University Medical Center
New Orleans, Louisiana, United States, 70112