Status:

COMPLETED

Flouro-Gem in Adenocarcinoma of the Pancreas (GEFLUPAN)

Lead Sponsor:

Menoufia University

Conditions:

Cancer of Pancreas

Chemotherapy Effect

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

In this study, the investigators designed a treatment regimen including the most active agents in pancreatic cancer which are gemcitabine and fluorouracil to be tested as a first line treatment. This ...

Detailed Description

Metastatic cancer pancreas has been a challenge for oncologists over the years. It is a disease of limited survival and a very poor response to treatment. The median overall survival at five years is ...

Eligibility Criteria

Inclusion

  • Histopathological evidence of adenocarcinoma of the pancreas
  • Radiological proof of metastatic disease as defined by AJCC

Exclusion

  • patients with poor performance status (ECOG 4)
  • patients with organ dysfunction defined as: creatinine more than 1.6 mg/dl or bilirubin more than 3 mg/dl
  • patients with end stage renal disease who are under regular dialysis
  • other histologies of pancreatic cancer
  • irresectable pancreatic cancer if not metatatic

Key Trial Info

Start Date :

February 20 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 9 2022

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04769414

Start Date

February 20 2021

End Date

July 9 2022

Last Update

August 8 2022

Active Locations (1)

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Menoufia University, Faculty of medicine

Shibīn al Kawm, Menoufia, Egypt, 32511