Status:

UNKNOWN

Evaluation of the Predictive Value of Blood Levels of Angiopoietin 1 and Endothelial Internal Tunica Cell Kinase 2 in Patients With Ovarian Cancer Treated With Chemotherapy Associated to Bevacizumab

Lead Sponsor:

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Collaborating Sponsors:

Ospedale SS Giovanni e Paolo, Venezia

Conditions:

Ovarian Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

This is a monocentric prospective observational pilot study of translational research in women with advanced ovarian epithelial cancer. The main purpose of this study is to evaluate the predictive val...

Eligibility Criteria

Inclusion

  • Patients ≥ 18 years old
  • Diagnosis of histologically confirmed advanced epithelial ovarian carcinoma
  • Women eligible for treatment with a chemotherapy regimen in combination to bevacizumab (Cohort A)
  • Women eligible for treatment with a chemotherapy regimen not associated to antiangiogenic drugs (Cohort B)
  • Evaluable disease according to RECIST 1.1 criteria
  • Patient informed consent signature prior to any study-specific procedure

Exclusion

  • History of other malignancy within 5 years prior to study entry (except for cutaneous basal cell carcinoma or adequately treated carcinoma in situ of the cervix ).

Key Trial Info

Start Date :

October 12 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2023

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT04770376

Start Date

October 12 2020

End Date

December 1 2023

Last Update

December 29 2022

Active Locations (1)

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1

Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, SSD Oncologia Medica Addarii

Bologna, Italy, 40138