Status:
UNKNOWN
Physiologic Ocular Changes During Pregnancy in Women With High Myopia.
Lead Sponsor:
Khon Kaen University
Conditions:
High Myopia
Pregnancy Related
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
The prevalence of myopia is seemingly increasing, and it is one of the major causes of blindness. High myopia is defined as a refractive error with spherical equivalent exceeding -6 diopters and/or th...
Detailed Description
There are few studies of posterior ocular changes during pregnancy. A recent meta-analysis showed that the choroidal thickness and retinal vascular density were increased during pregnancy especially i...
Eligibility Criteria
Inclusion
- age \> 18 years
- high myopia: spherical equivalent \> 6 diopters and/or axial length \> 26.5 mm
- singleton pregnancy
- clear ocular media
- written inform consent
Exclusion
- high risk pregnancy such as pre-eclampsia, gestational diabetes mellitus, hyperthyroidism and asthma.
- history of retinal diseases such as macular edema and retinal vascular occlusion
- history of intraocular inflammation or endophthalmitis
- history of intraocular laser treatment
- history of intraocular surgery
- Withdrawal criteria
- childbirth before 34 weeks' gestation
- multifetal pregnancy was detected by ultrasound
- high risk pregnancy which could not follow the research protocol such as severe pre-eclampsia
- retinal diseases occur during the follow-up period such as central serous chorioretinopathy, retinal detachment and choroidal neovascularization
- significant ocular trauma during the follow-up period
- severe peripartum or postpartum complications such as thromboembolic disease and postpartum hemorrhage
Key Trial Info
Start Date :
July 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04773574
Start Date
July 1 2021
End Date
June 30 2025
Last Update
June 30 2021
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