Status:

COMPLETED

The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis

Lead Sponsor:

Lithuanian University of Health Sciences

Conditions:

Sepsis

Septic Shock

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effect of high-dose ascorbic acid on microcirculation in sepsis.

Detailed Description

Adult patients with septic shock were enrolled within 24 hours following admission to the Central Department of Intensive Care in Lithuanian University of Health Sciences Hospital Kaunas Clinics. Par...

Eligibility Criteria

Inclusion

  • Patients with sepsis or septic shock within the first 24 hours after ICU admission.

Exclusion

  • Age \< 18 years,
  • Pregnancy,
  • Advanced malignancy,
  • History of kidney stone, glucose-6-phosphate deficiency, hemochromatosis, or solid organ transplantation,
  • Oral mucosal inflammation or injury or technical difficulties in obtaining sublingual images.

Key Trial Info

Start Date :

January 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 31 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04773717

Start Date

January 1 2019

End Date

January 31 2021

Last Update

March 3 2021

Active Locations (1)

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Lithuanian University of Health Sciences Hospital Kaunas Clinics

Kaunas, Lithuania