Status:
TERMINATED
Primary Prophylaxis for Spontaneous Bacterial Peritonitis
Lead Sponsor:
Changi General Hospital
Conditions:
Decompensated Cirrhosis
Small Bowel Bacterial Overgrowth Syndrome
Eligibility:
All Genders
18-70 years
Phase:
PHASE2
PHASE3
Brief Summary
Patient with liver cirrhosis commonly have co-existing small bowel bacterial overgrowth (SIBO) yet may be asymptomatic. It is unclear as to the value of treating SIBO in asymptomatic individuals. Cirr...
Eligibility Criteria
Inclusion
- Decompensated liver cirrhosis (Childs B \& C) with ascites.
- Established diagnosis of SIBO
Exclusion
- Known allergy to treatment drugs
- Inability to undergo test confirm the success of SIBO eradication;
- Pregnant or lactating women
- Terminal malignancy.
- Untreated Viral Hepatitis
- Alcoholic Liver disease with ongoing drinking.
- Respiratory Failure
- Recent antibiotics and proton-pump inhibitor within 30 days
Key Trial Info
Start Date :
November 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2023
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT04775329
Start Date
November 1 2020
End Date
January 1 2023
Last Update
January 6 2023
Active Locations (1)
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1
Wong Yu Jun
Singapore, Singapore, 529889