Status:

RECRUITING

Therapeutic Orientation Test in Thrombotic Microangiopathy

Lead Sponsor:

University Hospital, Montpellier

Conditions:

Thrombotic Micro-angiopathy

Eligibility:

All Genders

Up to 90 years

Phase:

NA

Brief Summary

Haemolytic and Uraemic Syndrome (HUS) is a serious disease requiring rapid diagnosis and management. The atypical HUS diagnosis has been greatly improved by anti-CS antibody (Eculizumab) wich block al...

Eligibility Criteria

Inclusion

  • TMA with:
  • mechanic haemolytic anemia, undetectable haptoglobin, LDH\>1.5\*LNS
  • thrombopenia
  • acute kidney injury TMA on native kidney or in post-transplantation.

Exclusion

  • DIVC patients
  • plasma exchange during 1 month before sample collection
  • treatment by Eculizumab before sample collection
  • no consent
  • not beneficiary of a social security
  • pregnancy or breastfeeding
  • patient Under guardianship

Key Trial Info

Start Date :

April 3 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 3 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04777435

Start Date

April 3 2021

End Date

April 3 2027

Last Update

July 23 2025

Active Locations (20)

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Page 1 of 5 (20 locations)

1

CHU de Bordeaux

Bordeaux, France

2

Site Médipôle Cabestany

Cabestany, France

3

Centre Nephrocare Castelnau-le-Lez

Castelnau-le-Lez, France

4

CHU de Grenoble

Grenoble, France