Status:

UNKNOWN

Intestinal Ultrasound Versus Double Balloon Enteroscopy (DBE) in Diagnosis of Malabsorption Syndrome

Lead Sponsor:

Assiut University

Conditions:

Malabsorption Syndrome

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Our aim is to compare between intestinal ultrasound and double-balloon enteroscopy in the diagnosis of malabsorption syndrome.

Detailed Description

Malabsorption is impaired absorption of nutrients caused by any disruption in the process of normal absorption. Normal nutrient absorption requires 3 steps: 1. Luminal and brush border processing (e....

Eligibility Criteria

Inclusion

  • Our study will include all patients referred to our unit with suspected malabsorption syndrome with one or more of the following will be included:
  • Clinically:
  • Chronic watery, diurnal, and nocturnal, bulky, and frequent diarrhea.
  • Steatorrhea.
  • Abdominal pain and /or distention.
  • Anorexia, nausea, vomiting.
  • Weight loss.
  • Anemic manifestations
  • Vitamin deficiencies manifestations (e.g Bleeding, bruising, glossitis Peripheral neuropathy) Malnutrition and growth retardation in children.
  • Extraintestinal manifestations (e.g Dermatitis herpetiformis, Ankylosing spondylitis, erythema nodosum).
  • Laboratory: routine blood tests that may reveal anemia, high CRP or low albumin, low calcium, and vitamin D level, high fecal calprotectin.

Exclusion

  • Mechanical gastrointestinal obstruction.
  • Pregnant ladies.
  • Those who fail to provide consent.
  • Those unfit for anesthesia (with cardio-pulmonary embarrassment )

Key Trial Info

Start Date :

June 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2023

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04777682

Start Date

June 1 2021

End Date

June 1 2023

Last Update

March 2 2021

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