Status:
UNKNOWN
Myofascial Pain Patients' Response to the Administration of Low Doses of Amitriptyline and Citalopram Compared With the Use of Bite Splint
Lead Sponsor:
University of Coimbra
Collaborating Sponsors:
Instituto de Investigación Biomédica de Salamanca
Conditions:
Muscle Type Temporomandibular Disorders
Myofascial Pain of the Masticatory Muscles
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
The aim of this study is evaluate the effectiveness of the use of antidepressants in the treatment of muscle type temporomandibular disorders, with a sample of 60 to 80 participants.
Detailed Description
Temporomandibular Disorders (TMDs) involve alterations of the temporomandibular joint (TMJ), masticatory muscles, and related structures. Epidemiologic data indicates that 33% of the general populati...
Eligibility Criteria
Inclusion
- Patients treated at the Centro Hospitalar e Universitário de Coimbra (CHUC);
- Patients who, according to the diagnostic Criteria for Temporomandibular disorder (DC/TMD) , present Myofascial pain in the masticatory muscles for more than 6 months;
- Adult patients
Exclusion
- Under 18 years old;
- Pregnants,
- Patients who have related adverse effects to the citalopram and/or amitriptyline;
- Patients presenting severe diseases like coronary pathology, renal insufficiency, active cancer, respiratory insufficiency;
- Patients who have been treated to myofascial pain before
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2021
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04777838
Start Date
March 1 2021
End Date
May 1 2021
Last Update
March 2 2021
Active Locations (1)
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1
CHUC - Centro Hospitalar e Universitário de Coimbra
Coimbra, Portugal, 3000-075