Status:
RECRUITING
Long-term Remote Ischemic Preconditioning Improves Myocardial Perfusion and Prognosis of Patients After CABG
Lead Sponsor:
Henan Institute of Cardiovascular Epidemiology
Conditions:
Coronary Disease
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Remote Ischemic preconditioning (RIPC) has been reported to improve myocardial microcirculation, promote collateral circulation recruitment, and improve myocardial perfusion in patients.Two large rand...
Detailed Description
A total of 210 patients were randomly divided into three groups according to the inclusion and exclusion criteria, with 70 patients in each group. Experimental Group 1: The patient underwent one RIP...
Eligibility Criteria
Inclusion
- Three coronary artery lesions, CABG surgery was planned
Exclusion
- The patients could not tolerate ripc;
- peripheral vascular disease affecting upper limbs
- Acute myocardial infarction complicated with cardiogenic shock，in recent 30 days,
- Emergency cases
- Severe structural heart disease and severe arrhythmia ；
- The uncontrolled systolic blood pressure and diastolic blood pressure of severe hypertension were 180 mmHg and 120 mmHg respectively;
- Severe liver, renal and pulmonary disease
- Mental disorder can't cooperate;
- Inability to give informed consent；
- Patients on glibenclamide or nicorandil, as these medications may interfere with RIC
- pregnant;
Key Trial Info
Start Date :
March 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT04779008
Start Date
March 10 2021
End Date
December 1 2026
Last Update
September 18 2025
Active Locations (1)
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1
Fuwai central China cardiovascular Hospital
Zhengzhou, Henan, China