Status:

COMPLETED

Patent Foramen Ovale Closure in Older Patients

Lead Sponsor:

Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec

Collaborating Sponsors:

Toronto General Hospital

Montreal Heart Institute

Conditions:

Patent Foramen Ovale

Ischemic Stroke

Eligibility:

All Genders

60+ years

Brief Summary

* Describe the baseline and procedural characteristics of older patients undergoing PFO closure due to cryptogenic embolism. * Assess the long-term follow-up of this cohort, focusing on neurological e...

Detailed Description

In patients with cryptogenic stroke, up to 4 randomized trials and subsequent meta-analyses have recently shown a significant reduction in recurrent ischemic stroke events following percutaneous closu...

Eligibility Criteria

Inclusion

  • Patients older than 60 years who have experienced a previous paradoxical embolism (stroke, transient ischaemic attack or peripheral embolism) of unknown origin and underwent transcatheter PFO closure.

Exclusion

  • PFO closure indication other than paradoxical embolism (example: platypnea orthodeoxia syndrome).
  • Surgical PFO closure.

Key Trial Info

Start Date :

April 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2021

Estimated Enrollment :

350 Patients enrolled

Trial Details

Trial ID

NCT04780022

Start Date

April 1 2021

End Date

December 1 2021

Last Update

March 2 2022

Active Locations (1)

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CRIUCPQ

Québec, Quebec, Canada, G1V 4G5