Status:
UNKNOWN
Characterization and Outcome of Children With Leukodystrophy: An Observational Study at Sohag University Hospital
Lead Sponsor:
Sohag University
Conditions:
Children With Leukodystrophy
Eligibility:
All Genders
Up to 18 years
Brief Summary
Leukodystrophies are heterogeneous genetic disorders characterized by the selective involvement of white matter in the central nervous system (CNS) (1, 2). Inherited leukodystrophies are diseases of t...
Eligibility Criteria
Inclusion
- The patients fulfilling all the following criteria will be included:
- Age ≤ 18 years.
- The presence of typical clinical, biochemical, and neuroimaging features of leukodystrophies.
Exclusion
- 1- Children who have coexistent genetic disorders. 2- Children who have cerebral malformations. 3- History of perinatal asphyxia. 4- History of head trauma or intracranial hemorrhage. 5- Acquired CNS myelin disorders, such as multiple sclerosis and related acquired demyelinating processes, infectious and post-infectious white matter damage, toxic injuries and non-genetic vascular insults.
Key Trial Info
Start Date :
March 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2023
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04781010
Start Date
March 1 2021
End Date
March 31 2023
Last Update
March 4 2021
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