Status:

UNKNOWN

The Study of Microglia/Macrophages Involved Dynamic Evolution of Glioma Microenvironment and the Function and Visualization of Targeted Molecules of Glioma

Lead Sponsor:

Huashan Hospital

Conditions:

Glioma

Eligibility:

All Genders

18-80 years

Brief Summary

establishment of glioma microenvironment cell dynamic evolution database reveal the mechanism of GIM promoting malignant transformation of glioma cells reveal the dynamic regulation process of immune ...

Detailed Description

To collect tissue samples from different stages of glioma evolution and establish a high-quality high-throughput sequencing database of immune microenvironment cells, so as to lay a data foundation fo...

Eligibility Criteria

Inclusion

  • The patients with glioma in the Department of Neurosurgery of Huashan Hospital Affiliated to Fudan University who meet the following three conditions can be enrolled
  • They were 18-80 years old, male and female;
  • The pathological results of frozen section during operation were gliomas (20 cases of who grade II, II and IV, respectively);
  • Tissue (6 mm \* 6 mm) can be used for cell sorting on the basis of not affecting clinical routine diagnosis;
  • Sign informed consent.

Exclusion

  • Patients who meet any of the following criteria will not be included in this study:
  • Participants in other clinical trials;
  • Pregnant women.

Key Trial Info

Start Date :

November 9 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04781764

Start Date

November 9 2020

End Date

December 31 2022

Last Update

March 24 2021

Active Locations (1)

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Huashan Hospital,Fudan University

Shanghai, China, 200040