Status:

UNKNOWN

DNA Damage and Oxidative Stress in Hospitalized COVID-19 Patients

Lead Sponsor:

University of Vienna

Collaborating Sponsors:

SMZ-Ost Donauspital

Conditions:

Covid19

Eligibility:

All Genders

40+ years

Brief Summary

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic challenging health systems worldwide. While there is a clear corre...

Eligibility Criteria

Inclusion

  • Covid 19 group:
  • gender: female/male
  • age: ≥40 years
  • patients admitted at the emergency department
  • COVID-19 suspected patients
  • able to give written informed consent

Exclusion

  • children (≤ 18 years) and adults 19-39 years
  • not hospitalized, but confirmed COVID-19 patients (outpatients)
  • patients without definitive COVID-19 confirmation
  • Control group:
  • Inclusion criteria:
  • gender: female/male
  • age: ≥40 years
  • absence of severe illnesses/serious diseases
  • able to give written informed consent
  • Exclusion criteria:
  • children (≤ 18 years) and adults 19-39years
  • any current or past clinically significant pathology/disease (comorbidity) such as:
  • Malignancies
  • Cardiovascular diseases
  • Diabetes mellitus (I and II)
  • Obesity class III (BMI \>40)
  • Other severe diseases (e.g. renal, hepatic, thyroid disease, bone metabolic diseases, rheumatoid osteoarthritis, human immunodeficiency syndrome, …)
  • Influenza group:
  • Inclusion criteria:
  • gender: female/male
  • age: ≥40 years
  • patients admitted at the emergency department
  • influenza suspected patients
  • able to give written informed consent
  • Exclusion criteria:
  • children (≤ 18 years) and adults 19-39 years
  • patients without definitive influenza confirmation

Key Trial Info

Start Date :

November 19 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2021

Estimated Enrollment :

135 Patients enrolled

Trial Details

Trial ID

NCT04784468

Start Date

November 19 2020

End Date

September 30 2021

Last Update

March 9 2021

Active Locations (1)

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Klinik Donaustadt

Vienna, Austria, 1220