Status:
RECRUITING
Timing of Endoscopic Intervention for Acute Variceal Hemorrhage: an RCT
Lead Sponsor:
Jinling Hospital, China
Collaborating Sponsors:
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
The first affiliated Hospital of Nanjing Medical University, Jiangsu Province
Conditions:
Acute Upper Gastrointestinal Hemorrhage
Cirrhosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Acute variceal upper gastrointestinal hemorrhage remains a hot potato in cirrhotic patients. The purpose of this study is to figure out whether urgent endoscopy (within 6h after gastroenterological co...
Detailed Description
Study design The study protocol observes the Standard Protocol Items rules: Recommendations for Interventional Trials (SPIRIT) 2013. The leader of the sponsoring organization strictly implements over...
Eligibility Criteria
Inclusion
- (I) patients who have pathological or clinical and imaging evidence indicating a diagnosis of cirrhosis; (II) patients with clinical symptoms associated with AVH (hematemesis, melena or hematochezia) before admission or during hospitalization; (III) patients who are hemodynamically stable before or after initial fluid resuscitation.
Exclusion
- (I) pregnancy; (II) lactation; (III) less than 18 years; (IV) patients with a history of taking anticoagulant or antiplatelet drugs within 2 weeks prior to admission.
Key Trial Info
Start Date :
April 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 28 2026
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT04786743
Start Date
April 20 2021
End Date
February 28 2026
Last Update
November 24 2025
Active Locations (4)
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1
Affiliated Jinling Hospital, Medical School of Nanjing University
Nanjing, Jiangsu, China, 210002
2
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School
Nanjing, Jiangsu, China, 210008
3
First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China, 210029
4
The Affiliated Wuxi People's Hospital of Nanjing Medical University
Wuxi, Jiangsu, China, 214043