Status:

COMPLETED

Renal Involvement in Hospitalized Children With COVID-19

Lead Sponsor:

Hamad Medical Corporation

Conditions:

Acute Kidney Injury

Covid19

Eligibility:

All Genders

1-14 years

Brief Summary

Covid-19 is an important human and animal pathogen, it mostly causes respiratory and gastrointestinal symptoms. Clinical features range from a common cold to severe diseases such as severe acute respi...

Detailed Description

COVID-19 usually causes respiratory and gastrointestinal symptoms, Clinical features range from a common cold to severe diseases such as bronchitis, pneumonia, severe acute respiratory distress syndro...

Eligibility Criteria

Inclusion

  • All pediatric patients with COVID-19 were admitted to Hamad Hospital from (0 to 14) years, using the electronic medical records (Cerner), over that time period (from March 1, to January 1, 2021), with one of the following:
  • Proteinuria: (≥1+) on dipstick analysis.
  • Hematuria: ≥ 5 RBC/HPF.
  • Sterile Pyuria: ≥ 5 WBC/HPF or ≥10 WBC/mm3 with negative urine culture (44).
  • Hypernatremia :\> 145meq/l.
  • Hyponatremia: \< 135 meq/l.
  • Hypokalemia :\< 3.5meq/l.
  • Metabolic acidosis (ph \<7.35).
  • Elevated serum creatinine :\> upper limit of reference interval (ULRI) values.
  • Elevated serum urea: \> 7 mmol/l.
  • Urine specific gravity (SG) \<1.003.

Exclusion

  • \* Patient with previous chronic kidney diseases.

Key Trial Info

Start Date :

March 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2021

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT04788394

Start Date

March 1 2021

End Date

December 31 2021

Last Update

July 25 2023

Active Locations (1)

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1

Hamad General corporation

Doha, Qatar, 3050