Status:

UNKNOWN

The Effect of Different Remineralizing Agents on White Spot Lesions and Dental Plaque During Orthodontic Retention

Lead Sponsor:

University of Malaya

Conditions:

Orthodontic Appliance Complication

Eligibility:

All Genders

16-40 years

Phase:

NA

Brief Summary

Dental caries is a decay process that breaks down the tooth. The earliest clinical signs of active dental caries is seen as 'white spot lesions' (WSLs). WSLs causes porosity below the tooth surface as...

Detailed Description

Rationale of the study : Currently there is insufficient evidence on the most effective regime of fluoride application to regress post orthodontic WSLs and how it affects the quality and quantity of ...

Eligibility Criteria

Inclusion

  • Subjects on multibracket fixed appliance treatment
  • Subjects with 2 or more bracketed surfaces with labial subsurface WSLs from
  • upper right permanent canine (13) to upper left permanent canine (23) with an ICDAS II score of 1 and 2 will be selected.
  • Indicated for thermoform or vacuum formed retainers on the upper arch.

Exclusion

  • Systemic diseases or any physical anomalies.
  • Subjects with intention to move out from Klang Valley area for the next 1.5 years.
  • Periodontal diseases (pocket depth of more than 3mm).
  • Smoker.
  • Severe fluorosis or any enamel abnormalities.
  • Antimicrobial agents or antibiotic therapy within the past 3 months.
  • Orthognathic surgery cases, cleft lip and palate.
  • Single arched lower fixed orthodontic treatment.
  • Milk protein and benzoate preservatives (a common preservatives) allergies.

Key Trial Info

Start Date :

March 17 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04788550

Start Date

March 17 2021

End Date

December 31 2022

Last Update

October 22 2021

Active Locations (1)

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Postgraduate Orthodontic Clinic, Faculty Of Dentistry, University Of Malaya

Kuala Lumpur, WP Kuala Lumpur, Malaysia, 50603