Status:
COMPLETED
Effects of Non-calorie Sweeteners, Mono- and Disaccharides on Intestinal Barrier Function
Lead Sponsor:
University of Vienna
Conditions:
Dietary Habits
Endotoxemia
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The aim of the present study is to determine the effect of non-nutritive sweeteners on intestinal barrier function and inflammatory markers in healthy subjects in comparison to mono- and disaccharides...
Detailed Description
In the intervention study normal weight participants will receive beverages sweetened with non-nutritive sweeteners, mono- and disaccharides for a defined number of days. Before and after intervention...
Eligibility Criteria
Inclusion
- No known history of metabolic diseases/disorders
- BMI \<25 kg/m2
Exclusion
- Food allergies or intolerances (esp. fructose intolerance and malabsorption)
- Chronic disease of the gastrointestinal tract
- Renal insufficiency
- Taking drugs affecting lipid or glucose metabolism
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT04788680
Start Date
March 1 2021
End Date
December 31 2022
Last Update
November 1 2023
Active Locations (1)
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1
University of Vienna
Vienna, Austria, 1090