Status:
UNKNOWN
The Adjunctive Use of Melatonin Therapy in the Treatment of Obese Periodontitis Patients (Clinical and Immunological Study).
Lead Sponsor:
University of Baghdad
Conditions:
Periodontal Diseases
Eligibility:
All Genders
27-54 years
Phase:
PHASE1
PHASE2
Brief Summary
To evaluate the effect of adjunctive systemic administration of melatonin to mechanical non- surgical periodontal therapy in obese patients with periodontitis.
Detailed Description
Periodontitis defined as destruction of periodontal tissue caused by specific microorganisms resulting of pocket formation, recession and mobility.Obesity known to increase the host tolerance by influ...
Eligibility Criteria
Inclusion
- The study involve three groups: the first one is control (healthy normal weight group).
- The second one is experimental group which must have the following criteria:
- 1-latest sleep, obese patients diagnosed to have periodontitis with probing pocket depth ≥ 5mm, 2-patients able to follow the required instruction.
- \-
Exclusion
- 1-individuals having night work shifts. 2-patients wearing removable partial dentures and undergoing orthodontic treatment.
- 3-patient taking anti-inflammatory drugs, antibiotics, immunosuppressant or oral contraceptives since last 3 months.
- 4-paients with diabetic mellitus, liver diseases, autoimmune diseases and osteoporosis.
- 5-pregnant or lactating women. 6-cancer patient. 7-smoker patient.
- \-
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2022
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04788979
Start Date
April 1 2021
End Date
February 1 2022
Last Update
March 9 2021
Active Locations (1)
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1
university of Baghdad
Baghdad, Iraq