Status:
UNKNOWN
Three-dimensional Choroidal Vascularity Index in Common Fundus Diseases
Lead Sponsor:
Renmin Hospital of Wuhan University
Conditions:
Choroid
Eligibility:
All Genders
10-75 years
Brief Summary
Explore the changes of choroidal blood perfusion in common fundus diseases by three-dimensional choroidal vascularity index, an optical coherence tomography (OCT) parameter.
Detailed Description
Compared with the choroidal vascularity index on a single OCT image, the three-dimensional choroidal vascularity index can evaluate the choroidal changes of chorioretinal diseases as a whole. In this ...
Eligibility Criteria
Inclusion
- Healthy participants (1) Inclusion Criteria: 1) without systemic diseases such as diabetes and hypertension 2) best corrected visual acuity BCVA ≥ 1.0 3) aged 18 years or older (2) Exclusion criteria: 1) equivalent spherical refraction between -3 diopters and + 1.0 diopters 2) any visible lesions in the retina, optic nerve, or choroid 3) history of refractive or intraocular surgery
- Myopia group (1) Inclusion Criteria: 1) equivalent spherical refraction greater than -0.25 diopters 2) without systemic diseases such as diabetes and hypertension 3) Best corrected visual acuity (BCVA) ≥ 1.0 4) aged 10 years or older (2) Exclusion criteria: 1) history of refractive or intraocular surgery 2) history of laser therapy 3) other systemic diseases that may affect the choroid
- Central serous chorioretinopathy (CSC) group (1) Inclusion Criteria: 1) a diagnosis of CSC (2) Exclusion criteria: 1) high myopia or hyperopia (greater than 26 or +3 diopters of refractive error) 3) other systemic diseases that may affect the choroid 4) any other associated retinal pathology 5) history of refractive or intraocular surgery
Exclusion
Key Trial Info
Start Date :
March 4 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 10 2024
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04790084
Start Date
March 4 2021
End Date
March 10 2024
Last Update
March 10 2021
Active Locations (1)
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1
Renmin Hospital of Wuhan University
Wuhan, Hubei, China, 430000