Status:
COMPLETED
Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension
Lead Sponsor:
Prisma Health-Upstate
Conditions:
Hypertension in Pregnancy
Eligibility:
FEMALE
18+ years
Phase:
PHASE4
Brief Summary
A significant number of pregnancies are complicated by hypertensive disorders. Hypertension often worsens in the postpartum period and many women need started on medications. Currently, recommended me...
Eligibility Criteria
Inclusion
- Postpartum women with a diagnosis of chronic hypertension, gestational hypertension, or preeclampsia
- Delivery at or beyond 20 weeks' gestation
- Need for antihypertensive therapy, defined as blood pressure \>/= 150 mmHg systolic and/or 100 mmHg diastolic on two occasions four hours apart or isolated blood pressure \>160/110 mmHg
- English or Spanish-speaking
- Age 18 years or older
Exclusion
- Use of antihypertensive prior to delivery (for any indication)
- Allergy to nifedipine ER or amlodipine
- Persistent tachycardia (as defined by the treatment team)
Key Trial Info
Start Date :
April 9 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 25 2023
Estimated Enrollment :
175 Patients enrolled
Trial Details
Trial ID
NCT04790279
Start Date
April 9 2021
End Date
January 25 2023
Last Update
October 28 2024
Active Locations (1)
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1
Greenville Memorial Hospital
Greenville, South Carolina, United States, 29605