Status:
COMPLETED
Impact of 4 Months of Exercise Changes of Heart Health-related Epigenetic Markers in Healthy, Sedentary Individuals
Lead Sponsor:
Paracelsus Medical University
Collaborating Sponsors:
Ludwig Boltzmann Institute for Digital Health and Prevention
Conditions:
Sedentary Behavior
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
We aim to analyze the impact of a single acute exercise intervention (ergometry) on the expression pattern of specific heart health related miRNAs in healthy, previously sedentary participants, and ho...
Detailed Description
Exercise induced changes in heat health related miRNA expression pattern are analyzed in plasma samples collected at rest and immediately after the completion of an all-out ergo spirometry test, condu...
Eligibility Criteria
Inclusion
- \<150min physical activity per week
- \>18 years of age
- male and female
- signed inform consents
Exclusion
- acute or chronic cardiovascular diseases, exempt arterial hypertension (systolic blood pressure \>140 mmHg and diastolic blood pressure \>90 mmHg in untreated and medical treated subjects)
- acute or chronic lung disease
- Alcohol (\>30g/day) or drug abuse
- Adipositas grad 2 (BMI \>35kg/m²)
- Orthopedic limitations to exercise capacity
- pregnant or breast feeding women
Key Trial Info
Start Date :
July 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2024
Estimated Enrollment :
46 Patients enrolled
Trial Details
Trial ID
NCT04791306
Start Date
July 1 2021
End Date
March 31 2024
Last Update
April 4 2024
Active Locations (1)
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1
Department of Sports Medicine, Prevention and Rehabilitation Paracelsus Medical University
Salzburg, Austria, 5020