Status:

COMPLETED

Potential Role of Donor-derived Cell-Free DNA as a Biomarker in Cardiac Allograft Vasculopathy

Lead Sponsor:

Puerta de Hierro University Hospital

Conditions:

Cardiac Allograft Vasculopathy

Eligibility:

All Genders

18-80 years

Brief Summary

Cross-sectional study. We will prospectively obtain ddcf-DNA levels in all patients who undergo routine coronary angiography \> 1 year after HT. Our main goal is to evaluate the performance of Donor-d...

Eligibility Criteria

Inclusion

  • Patients over 18 and under 80 years old, HT \> 1 year ago

Exclusion

  • Patients under 18 or over 80 years old
  • Multiorgan transplant
  • History of acute cellular rejection ≥ 1R or antibody mediated rejection in the previous 6 months
  • Concomitant infection by CMV

Key Trial Info

Start Date :

January 10 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 15 2021

Estimated Enrollment :

94 Patients enrolled

Trial Details

Trial ID

NCT04791852

Start Date

January 10 2019

End Date

April 15 2021

Last Update

September 16 2021

Active Locations (1)

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1

University Hospital Puerta de Hierro

Majadahonda, Madrid, Spain, 28222