Status:

UNKNOWN

Neuromuscular Electrical Stimulation Study

Lead Sponsor:

Nottingham University Hospitals NHS Trust

Conditions:

Sarcopenia

Eligibility:

All Genders

65+ years

Phase:

NA

Brief Summary

In this study, the investigators will use feasibility RCT design to determine whether it is justifiable to conduct a large-scale clinical trial of neuromuscular electrical stimulation with or without ...

Detailed Description

In frail elderly people with existing sarcopenia, muscle mass, muscle strength and muscle function during immobility after lower limb fractures are impaired and affect their functional abilities to ac...

Eligibility Criteria

Inclusion

  • \>/=65 years
  • Hospitalised due to incident fragility fracture (hip, spine, pelvis, rib, upper limb, lower limb)
  • Immobile 72 hours after admission or completion of surgery whichever is the later.
  • Predicted date of discharge \>/= 7 days after recruitment

Exclusion

  • Unable to give valid informed consent
  • Residence outside catchment area of hospital (likely to be moved during the study period)
  • Unable to communicate in English sufficiently to participate in neuromuscular electrical stimulation.
  • Implanted medical device (e.g. pacemaker)
  • Any other contraindications to neuromuscular electrical stimulation (e.g. injury to the stimulation sites)
  • Leg amputation or any pre-injury conditions affecting a leg unilaterally such as hemiparesis
  • Dysphagia for liquids
  • Protein supplementation clinically indicated and prescribed
  • End stage renal failure
  • Obesity (BMI\>30)
  • End of life, for any reason
  • Any other clinical reason why rehabilitation is not clinically indicated
  • Within 10 days of being symptom free having been COVID-19 positive (PCR testing or clinical criteria), or other barrier nursed patients
  • Lactose intolerance

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2022

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT04792307

Start Date

April 1 2021

End Date

June 30 2022

Last Update

March 10 2021

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