Status:
COMPLETED
Memantine in Body Focused Repetitive Behaviors
Lead Sponsor:
University of Chicago
Conditions:
Trichotillomania (Hair-Pulling Disorder)
Dermatillomania
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This study is 8 weeks long and involves subjects taking memantine or placebo. If they are randomly assigned to the memantine arm and are eligible to participate in the study, they will begin by taking...
Detailed Description
The goal of the proposed study is to evaluate the efficacy and safety of memantine in 100 subjects with DSM-5 trichotillomania (TTM) or skin picking disorder (SPD). The hypothesis to be tested is tha...
Eligibility Criteria
Inclusion
- men and women age ≥18 years;
- current DSM-5 trichotillomania or skin picking disorder; and
- Ability to understand and sign the consent form.
Exclusion
- Unstable medical illness based on history or clinically significant abnormalities on baseline physical examination
- Current pregnancy or lactation, or inadequate contraception in women of childbearing potential
- Subjects considered an immediate suicide risk based on the Columbia Suicide Severity rating Scale (C-SSRS) (www.cssrs.columbia.edu/docs)
- Past 12-month DSM-5 diagnosis of psychosis, bipolar disorder, mania, or a substance or alcohol use disorder
- Illegal substance use based on urine toxicology screening
- Stable dose of medications for at least the past 3 months
- Previous treatment with memantine
- Cognitive impairment that interferes with the capacity to understand and self-administer medication or provide written informed consent
Key Trial Info
Start Date :
June 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 8 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04792645
Start Date
June 15 2021
End Date
July 8 2022
Last Update
September 19 2024
Active Locations (1)
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1
University of Chicago
Chicago, Illinois, United States, 60637