Status:

WITHDRAWN

Buprenorphine Induction for Fentanyl Dependent Opioid Users

Lead Sponsor:

Milton S. Hershey Medical Center

Conditions:

Opioid Dependence Fentanyl

Eligibility:

All Genders

18-99 years

Phase:

EARLY_PHASE1

Brief Summary

The overall goal of this pilot study is to characterize illicit fentanyl and combination fentanyl and opioid dependence explicitly, by assessing physiologic barriers to effective buprenorphine inducti...

Detailed Description

Illicit synthetic fentanyl is found in increasing proportions of illicit drug samples, and negatively influences how buprenorphine is used on the street to help with subjective withdrawal symptoms. In...

Eligibility Criteria

Inclusion

  • 18 years of age or older
  • Diagnosis of opioid use disorder (OUD) as determined through routine clinical care
  • Positive for fentanyl on point of care urine drug screen
  • Ability to read, write, and comprehend English
  • Patients willing to start buprenorphine at the onset of treatment (e.g., clinical intake)
  • Patients who need to initiate a buprenorphine induction at home must have an operating smartphone or tablet device with video capability.

Exclusion

  • Initiating maintenance treatment that does not include MAT or switching to a maintenance treatment that does not include MAT (i.e.: detoxification and counseling treatment only without MAT, or planning to enter methadone treatment).
  • Judged by the evaluating physician or allied clinician to need a higher level of care (i.e.: residential or inpatient treatment)
  • Pregnant
  • Patients desiring to start methadone or naltrexone at the onset of treatment (e.g., clinical intake)
  • Patients who are unable to stay in the clinic for the induction period.

Key Trial Info

Start Date :

May 9 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 22 2024

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04794790

Start Date

May 9 2022

End Date

June 22 2024

Last Update

May 22 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

The Pennsylvania Psychiatric Institute

Harrisburg, Pennsylvania, United States, 17110