Status:

COMPLETED

A Study That Uses Data From Routine Eye Examinations of Patients Participating in Studies FIDELIO-DKD and FIGARO-DKD to Explore Whether Finerenone Can Delay the Progression of a Diabetes Complication That Affects the Eyes (Diabetic Retinopathy, DR)

Lead Sponsor:

Bayer

Conditions:

Diabetic Retinopathy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Diabetic retinopathy (DR) is a diabetes complication caused by damage to the small blood vessels inside the retina at the back of the eye. Diabetic retinopathy may cause mild vision problems or eventu...

Eligibility Criteria

Inclusion

  • Signed informed consent to participate in DeFineDR
  • Included in FIDELIO-DKD or FIGARO-DKD, and with DR as medical history
  • Documented NPDR in at least one eye, as documented by ophthalmological records within 6 months prior to baseline in FIDELIO-DKD or FIGARO-DKD, and up to one month after baseline in FIDELIO-DKD or FIGARO-DKD
  • An ophthalmological assessment available 6 month before or maximum 1 month after the baseline examination in FIDELIO-DKD or FIGARO-DKD, and at least one additional assessment afterwards.

Exclusion

  • Participants with PDR, macular edema or anterior segment complications present at baseline in FIDELIO-DKD or FIGARO-DKD in at least one eye.
  • Participants with any documentation of prior or planned retinal laser treatment, intravitreal injection or vitrectomy at baseline in FIDELIO-DKD or FIGARO-DKD in at least one eye.
  • Participants with any other retinal disease documented at baseline in FIDELIO-DKD or FIGARO-DKD in at least one eye that would likely interfere with the study objectives (e.g. neovascular age-related macular degeneration or retinal vein occlusion).

Key Trial Info

Start Date :

March 10 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2021

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04795726

Start Date

March 10 2021

End Date

June 30 2021

Last Update

November 2 2022

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Med Centre Diamedical 2013

Dimitrovgrad, Bulgaria, 6400

2

MHAT Sveta Karidad

Plovdiv, Bulgaria, 4004

3

MHAT Hadzhi Dimitar

Sliven, Bulgaria, 8800

4

MHAT Dr. Bratan Shukerov AD

Smolyan, Bulgaria, 4700