Status:
COMPLETED
Autologous Intraovarian Platelet Rich Plasma Treatment in Women With Poor Ovarian Response
Lead Sponsor:
Nadezhda Women's Health Hospital
Conditions:
Poor Ovarian Reserve
Eligibility:
FEMALE
30-46 years
Phase:
NA
Brief Summary
Reproductive age women diagnosed with poor ovarian response (POR) based on Bologna criteria with a history of at least two prior failed ICSI cycle will be recruited for the study. Antral follicle coun...
Detailed Description
Reproductive age women diagnosed with POR based on Bologna criteria with a history of at least two prior failed intracytoplasmic sperm injection (ICSI) cycle will recruited for the study. Antral folli...
Eligibility Criteria
Inclusion
- Patients diagnosed with POR based on Bologna criteria and with a history of at least two prior failed ICSI cycles
- A previous assisted reproductive technology cycle with less than 3 oocytes (conventional stimulation protocol) and AFC \< 7
- The same ovarian stimulation protocol before and after the PRP treatment
Exclusion
- Age over 46 years,
- Body mass index (BMI) ≥ 30 kg/m2,
- Presence of pregnancy
- Uncontrolled endocrine disorders (polycystic ovary syndrome and others)
- Parental genetic and chromosomal disorders,
- Immunological disorders
- Cancer diagnostics
Key Trial Info
Start Date :
March 16 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 4 2021
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04797377
Start Date
March 16 2021
End Date
September 4 2021
Last Update
April 6 2022
Active Locations (1)
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1
Nadezhda Women's Health Hospital
Sofia, Bulgaria, 1373