Status:

RECRUITING

Treatment of Multiple Gingival Recession Defects Using a New Xenogenic Collagen Membrane Compared to Connective Tissue Graft: a Randomized Controlled Split-mouth Clinical Study

Lead Sponsor:

Centre Hospitalier Universitaire de Nice

Conditions:

Gingival Recession

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Limitation of donor site and significant postoperative morbidity are often described in connective tissue graft. We want to show if mucogain matrix used in tunnel technique to recover RTI Cairo recess...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Patient with 3 contiguous, symmetrical and bilateral RTI Cairo gingival recessions (Miller Class 1) (i.e. 6 recessions)
  • Patient non-smoker
  • Patient affiliated to social security
  • Patient signed informed consent.
  • Exclusion criteria:
  • Patient with or having presented an acute or chronic severe cardiovascular, kidney, liver, gastrointestinal, allergic, endocrine, neuropsychiatric pathology, developed cancer of the upper aero digestive tract treated with radiotherapy
  • Patient with severe hemorrhinopathy
  • Patient treated with oral retinoids, bisphosphonates, oral or anticonvulsants
  • Patient who has taken steroidal or non-steroidal anti-inflammatory therapy, anti-cancer or immunosuppressive chemotherapy within the last 6 months.
  • Patient with contraindication to necessary and pre-, per- or post-operative treatments
  • Follow-up of the patient seemed difficult by the investigator
  • Patient with insufficient oral hygiene incompatible with oral surgery

Exclusion

    Key Trial Info

    Start Date :

    July 24 2023

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    January 1 2025

    Estimated Enrollment :

    20 Patients enrolled

    Trial Details

    Trial ID

    NCT04800250

    Start Date

    July 24 2023

    End Date

    January 1 2025

    Last Update

    February 9 2024

    Active Locations (1)

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    1

    CHU de Nice

    Nice, Provence-Alpes-Côte d'Azur Region, France, 06000