Status:
COMPLETED
Commercial Typhoid Tests Validation Trial
Lead Sponsor:
Foundation for Innovative New Diagnostics, Switzerland
Collaborating Sponsors:
Department for International Development, United Kingdom
Conditions:
Typhoid Fever
Eligibility:
All Genders
2-65 years
Brief Summary
Typhoid fever (typhoid) is an enteric bacterial infection caused by Salmonella enterica serovar Typhi (Salmonella Typhi; S. Typhi). It is one of the most common bacterial causes of acute febrile illne...
Detailed Description
Typhoid is an enteric disease caused by the bacterium Salmonella Typhi; it is estimated that 11 to 20 million people contract typhoid each year and 128 000 to 161 000 die from the disease; children un...
Eligibility Criteria
Inclusion
- \- Individuals aged 8 years of age to 65 years of age
- Body weight equals to or more than 8kgs
- History of fever or axillary temperature of \>37.50C for at least 3 consecutive days within the last 7 days prior to enrolment
- Clinical suspicion of enteric fever
- One of the following scenarios:
- Presents to outpatient department or Emergency Department
- Admitted to hospital within last 12 hours
- Able and willing to provide informed consent (and assent when required)
Exclusion
- Unwillingness to participate in the study
- Inability to provide the required volume of blood
- Unwillingness to provide blood
- Known non-infectious / Non typhoid Infectious causes of fever or other alternate diagnosis of fever
- Taking anticoagulant drugs
- Unconscious
Key Trial Info
Start Date :
October 25 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2021
Estimated Enrollment :
3091 Patients enrolled
Trial Details
Trial ID
NCT04801602
Start Date
October 25 2020
End Date
December 31 2021
Last Update
May 24 2022
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
KEMRI
Nairobi, Kenya
2
Aga Khan University
Karachi, Sindh, Pakistan