Status:
COMPLETED
Factors Influencing of Pulse Pressure Variation (PPV)
Lead Sponsor:
Southeast University, China
Conditions:
Haemodynamics
Fluid Responsiveness
Eligibility:
All Genders
18-80 years
Brief Summary
The investigators studied the predictive value of PPV in the patients with different influencing factors;and the method to improve the predictive value,which can improve the application of PPV in ICU.
Detailed Description
PPV can be used to predict fluid responsiveness in patients with circulatory shock.However, it is affected by many factors, which leads to the decrease of the applicability of PPV in ICU.Therefore, th...
Eligibility Criteria
Inclusion
- Patients requiring invasive mechanical ventilation
- Acute circulatory failure,defined as:systolic blood pressure \<90 mmHg or blood pressure in patients with previous hypertension lower than the baseline value\> 40 mmHg; vasoactive drugs are required to maintain blood pressure (mean arterial pressure\> 65 mmHg); with or without signs of hypoperfusion (oliguria\<0.5ml.kg-1.h-1 for at least 2 hours; arterial blood lactic acid\>2.5mmol.L-1; skin mottling)
Exclusion
- The age of the patient is less than 18 years old or more than 80 years old
- Refuse to sign the informed consent to join the group
- Atrial fibrillation and other arrhythmias that seriously affect the output per beat;
- With pregnancy
- Other situations where the clinician believes that the patient is not suitable for inclusion in the study
Key Trial Info
Start Date :
March 20 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 30 2022
Estimated Enrollment :
189 Patients enrolled
Trial Details
Trial ID
NCT04802668
Start Date
March 20 2021
End Date
July 30 2022
Last Update
January 10 2023
Active Locations (1)
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1
Ling Liu
Nanjing, Jiangsu, China, 210009