Status:
TERMINATED
"No-Touch" Radiofrequency Ablation for Small Hepatocellular Carcinoma (≤ 3cm): A Prospective Multicenter Study
Lead Sponsor:
Seoul National University Hospital
Collaborating Sponsors:
Samsung Medical Center
Chosun University Hospital
Conditions:
Radiofrequency Ablation
Microwave Ablation
Eligibility:
All Genders
20-85 years
Phase:
NA
Brief Summary
This study is a prospective multicenter study of the duration of treatment, the success rate, the frequency of complications, and the local recurrence rate of 12 months when Radio-frequency ablation t...
Detailed Description
1. Pre-treatment planning: The detailed plan of radio frequency ablation (RFA) will be implemented in accordance with the routine procedure of image evaluation prior to RFA. That is, after confirm...
Eligibility Criteria
Inclusion
- Agree to the protocol's requirements and submit a consent form
- 20 years old-85 years old
- Child-Pugh Class A or B7
- Among patients with cirrhosis, patients with hepatocellular carcinoma having a size of 1 cm-3 cm suspected of MDCT or MRI performed within 60 days are considered for radio-frequency ablation
- Patients who do not have a history of treatment for previous hepatocellular carcinoma, or who have a history of treatment for previous hepatocellular carcinoma, if recurrence has not been confirmed for at least 2 years after treatment
Exclusion
- the number of liver tumors is 3 or more
- the maximum size of the tumor exceeds 3 cm
- diffuse infiltrative type
- the tumor adheres to the portal vein or hepatic vein or biliary tract of 5 mm or more
- patients with previous medical history of hepatocellular cancer who have recurrent hepatocellular cancer within 2 years
- the tumor is not visible even under CEUS-fusion image guidance
- Child-Pugh class B8 or C
- in case of invasion of liver vessels due to malignant hepatocellular carcinoma
- severe coagulopathy
- multiple distant metastasis
- the situation where the probability of obtaining appropriate data suitable for the research purpose is very low
Key Trial Info
Start Date :
April 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 10 2021
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT04803890
Start Date
April 1 2019
End Date
March 10 2021
Last Update
March 18 2021
Active Locations (1)
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1
Seoul National University Hospital
Seoul, South Korea