Status:

RECRUITING

Proteomics Study of Mild Cognitive Impairment and Alzheimer's Disease

Lead Sponsor:

Guangzhou University of Traditional Chinese Medicine

Collaborating Sponsors:

Guangzhou Cadre Health Management Center

Conditions:

Alzheimer Disease, Early Onset

Protein; Disease

Eligibility:

All Genders

55+ years

Brief Summary

This study intends to adopt standardized and rigorous cross-sectional research, collect biological specimens (including blood, feces, urine, saliva and tongue coating) from eligible subjects, and use ...

Detailed Description

The problem of population aging is getting worse, the prevalence of senile dementia is increasing, and Alzheimer's disease (AD) is the most common type of dementia. There is no effective treatment for...

Eligibility Criteria

Inclusion

  • Older than 55-year-old,male or female.
  • patients meet the diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease(AD) or whose family members were diagnoed with AD
  • Complete self-rating scale for memory impairment (AD-8 scale)
  • Those who agree to participate in clinical research and sign informed consent.

Exclusion

  • Patients with acute cardiovascular and cerebrovascular diseases, acute infections (pneumonia, urinary tract infection, oral infection, digestive tract infection), severe renal dysfunction, and uremia;
  • Pregnant or lactating women;

Key Trial Info

Start Date :

June 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2026

Estimated Enrollment :

650 Patients enrolled

Trial Details

Trial ID

NCT04804618

Start Date

June 1 2021

End Date

June 30 2026

Last Update

November 15 2022

Active Locations (1)

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Guangdong Province Hospital of Tradtional Chinese Medicine

Guangzhou, Guangdong, China, 510120